ANGPT2 Recombinant Rabbit mAb (S-1768-2)
SKU: 43394545663

ANGPT2 Recombinant Rabbit mAb (S-1768-2)

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Description

ANGPT2 Recombinant Rabbit mAb (S-1768-2)Product Specification Host Rabbit Antigen ANGPT2 Synonyms Angiopoietin 2; ANG 2 Immunogen Recombinant Protein Location Secreted Accession O15123 Clone Number S 1768 2 Antibody Type Recombinant mAb Isotype IgG Application WB Reactivity Hu, Ms, Rt Positive Sample HepG2, HUVEC, TF 1, HeLa, mouse spleen, rat kidney Predicted Reactivity Bv, Pg, Dg Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage

Product Specification


Host Rabbit
Antigen ANGPT2
Synonyms Angiopoietin-2; ANG-2
Immunogen Recombinant Protein
Location Secreted
Accession O15123
Clone Number S-1768-2
Antibody Type Recombinant mAb
Isotype IgG
Application WB
Reactivity Hu, Ms, Rt
Positive Sample HepG2, HUVEC, TF-1, HeLa, mouse spleen, rat kidney
Predicted Reactivity Bv, Pg, Dg
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Unconjugated
Physical Appearance Liquid
Storage Buffer

PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 Hu, Ms, Rt

Background

Angiopoietin-2 (ANGPT2) is a member of the angiopoietin family and functions as a ligand for the TEK/TIE2 receptor, competing with angiopoietin-1 (ANGPT1) for binding sites. It plays a critical role in regulating angiogenesis and vascular remodeling. During embryonic development and tumorigenesis, ANGPT2 disrupts the vascular stability mediated by ANGPT1 and can induce endothelial cell apoptosis. Additionally, ANGPT2 is upregulated in various inflammatory diseases, where it contributes to the regulation of inflammation-related signaling pathways. In the tumor microenvironment, ANGPT2 synergizes with VEGF to promote endothelial cell migration and proliferation, acting as a pro-angiogenic signal. It also plays a role in lymphangiogenesis and serves as a prognostic biomarker in several cancers, including renal, liver, cervical, and gastric cancers.

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SKU: 43394545663

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4.5 ★★★★★
Based on 566 reviews
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Product Reviews
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Verified Purchase
Buyer
Louisville, US
★★★★★ 4
Normally amazing
Color: Spiky Ball (Blue, Orange), Size: Medium
We have purchased these slightly spiky dog balls several times for our very strong jaw heavy chewer dogs and they’ve been amazing. They don’t break down they don’t get torn apart the squeakers don’t even pop out of them. So we ordered another package because we’ve lost a few outside to the lawnmower… oops and the package that got delivered today had only one ball that squeaks and the other does not. THIS IS A PROBLEM ! Unfortunately my female dog got to the new squeaking ball first and my male got to the non-squeaking ball and he was NOT happy. Basically once they claim a ball it’s theirs and the other dogs don’t go near the ball they claimed. So he’s following my female around and every time she squeaks the ball and I’m just waiting for him to attempt to take it from her causing damage to her. Normally… These are amazingly fun, tough, durable but also squeaking balls (that’s rare in a tough ball) that my dogs absolutely love. This time just got a bad batch I guess. When they squeak the dogs LOVE them. After several months of play the squeaker might break inside of the ball but the ball never comes apart or gets damaged. And we as the owners love that they don’t break down are not able to be ripped or torn even by our very strong jawed and big jaw muscle dogs. They are also great for in the house play because they’re small enough that they fit completely inside our dog‘s mouth but obviously not small enough to get swallowed so when we throw them in the house for fetch the dogs can jump up and catch them fully in their mouth so they don’t cause any damage to the walls when they hit the walls. They’re not super heavy but they’re incredibly durable. Definitely worth the price especially if you have heavy chewers or big jaw muscle dogs.
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Reviewed in the United States on April 28, 2026
M
Verified Purchase
MADDY
Port Orchard, US
★★★★★ 5
Best fun indestructible toy
Color: Crinkle Duck (Yellow), Size: Large
Truly indestructible no matter how much our oittie tries. She has owned it for three months works at destroying every day with no success. She carries it everywhere. Best purchase for chewer, more fun than the popular rubber heavy duty toy. Do not hesitate your pup will thank you for this fun distraction.
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Reviewed in the United States on May 30, 2026
P
Verified Purchase
peter contino
Waukegan, US
★★★★★ 5
My dog loves this toy!
Color: Bunny (Gray), Size: Large, Color: Bunny (Gray), Size: Large
High quality, big toy, perfect for a medium to large size dog. After a few months of serious chewing I had to buy another one, but well worth the money! Rocky loves it.
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Reviewed in the United States on June 11, 2026
D
Verified Purchase
Denise Boyd
Carnegie, US
★★★★★ 4
Great toy but if your dog is an aggressive chewer, please think twice.
Color: Crinkle Chicken (Brown), Size: Large
I received this on May 23rd and on June 8th, after playing with this thing every day, our recently acquired 36 lb dog finally ripped it open and got out all the plastic and the squeaky part. Lily Belle will miss you, chicken. Lily loooooved this toy! She'd toss it in the air, chew on it, pull it with her teeth etc. but as much as she loved it, we won't replace it. It's just not durable enough for her. If your dog is an aggressive chewer, you might want to try a different toy. I hate that this lasted just a smidge over two weeks because Lily seemed to truly enjoy this toy. RIP, squeaky chicken!
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Reviewed in the United States on June 9, 2026
L
Verified Purchase
Literally doesn’t work
Los Angeles, US
★★★★★ 5
Great Value Toy
Color: Crinkle Duck (Blue), Size: Large, Color: Crinkle Duck (Blue), Size: Large
This toy has been one of my dog’s absolute favorites. He gets excited every time he sees it and will carry it around the house, toss it in the air, and keep himself entertained for a long time. The shape and texture seem perfect for him, and it quickly became one of his go-to toys over everything else in his basket. What I really like is that it holds up reasonably well for the price. It’s definitely not indestructible, and after a lot of play, it will sometimes start to rip—usually around the feet first since that’s where my dog tends to grab and chew the most. But honestly, considering how affordable it is, I don’t mind replacing it when needed. It’s inexpensive enough that rebuying feels worth it because he genuinely loves it that much. I’d rather keep buying a toy he is obsessed with than spend more on something that just sits untouched. It’s fun, cute, and keeps him happy, which is what matters most. Overall, I’d definitely recommend it for dogs who love plush toys and playful chewing.
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Reviewed in the United States on April 28, 2026

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